Geneticin Disulfate (G418) Powder
Catalog Number: AS-2011
CAS Number: 108321-42-2
MW: 692.71 g/mol
MF: C20H44N4O18S2
One special substance that comes from the bacteria Micromonospora rhodorangea is called geneticin disulfate (G418) powder. Although its toxicity prevents it from being used as an antibiotic to treat infections, it is valuable for cell culture. It performs the role of a selection agent specifically.
Geneticin Disulfate (G418) Powder binds to ribosomes to prevent the production of proteins. In contrast to eukaryotic cells, prokaryotic cells (bacteria) exhibit a stronger effect of this kind. This enables researchers to cultivate and select cells that are resistant to Geneticin Disulfate (G418) Powder in cell culture tests, while inhibiting those that are not.
For Laboratory Use Only.
Geneticin Disulfate (G418) Powder
Cat. Number AS-2011 CAS Number 108321-42-2 Additional CAS 49863-47-0 MDL Number MFCD00058314 Pubchem 310274067 Molecular Weight 692.71 g/mol Molecular Formula C20H44N4O18S2 Storage Temperature 4°C Form and Color Crystalline powder, white to off-white Solubility (10% in water) Clear Potency (dried basis) ≥ 720 µg/mg pH (20% in water) 4.6 – 6% Water content Max. 14% Ammonia ≤ 0.5%
